| 1. | Hormones promote expression ofhzfl , & hyacinthus zinc finger gene , during 24 hours cultured 外源激素在短时间内诱导锌指蛋白基因hzf1的高水平表达。 |
| 2. | In this study , we have identified four novel human krlipple - like zinc finger genes named znf325 , znf359 , zfp28 and znf323 本实验中,我们克隆了四个人类cys2 his2型锌指蛋白基因znf325 , znf359 , zfp28和znf323 。 |
| 3. | Taken together , these results indicate that these genes are members of zinc finger transcription factor family and may be involved in the development of multiple embryonic organs 综合这些基因的结构和表达特征,我们可以初步得出一个结论:它们编码的是参与多种人类胚胎器官发生的锌指转录调控因子。 |
| 4. | The complete human znf323 cdna sequence is 3179bp and contains a 1221 - bp open reading frame ( orf ) that encodes a 407 amino acid protein with a scan domain and 6 zinc finger c2i12 motifs Znf323长3179个碱基,含有一个长为1221个碱基的开放阅读框,编码一个长为407个氨基酸的蛋白质,它包含一个scan框和6个c2h2型锌指。 |
| 5. | The zfp28 cdna sequence is 4104 bp and contains a 2076 bp orf that encodes and 868 amino acids protein with an n - terminal signal peptide , two krab domain , and 14 c - termianal c2h2 zinc finger motifs Zfp28基因长4076个碱基,含8个外显子,在基因组dna上长18kb 。它编码的蛋白质全长868个氨基酸,含1个信号肽, 2个krab框和14个c2h2型的锌指。 |
| 6. | The cys2 / his2 type zinc finger genes are the single largest class of transcription factors in the human genome and many numbers of these krtlpple - like zinc finger genes have been found to be involved in cardiac development or cardiovascular diseases Cys2 his2型锌指蛋白基因是一类很大的转录调控因子家族基因,已发现很多cys2 his2型锌指蛋白参与了心脏发育和心血管疾病。 |
| 7. | The complete human znf359 cdna sequence is 3270 bp and contains a 1932 bp open reading frame ( orf ) that encodes a 643 amino acid protein with an n - terminal krab domain and 16 c - terminus zinc finger c2h2 motifs Znf359基因长3271个碱基,含6个外显子,在基因组dna上长18kb 。它编码的蛋白质全长643个氨基酸,含一个krab框, 16个c2h2型的锌指,在两者之间还有一个典型的中间重复序列。 |
| 8. | The znf360 mrnn a is 4031 bp , which spans 17 . 3 kb and is organized into eight exons . the preduced protein coded by znf360 gene contains 977 amino acids , including a krab motif , a scan motif , two sant motifs and ten krtlpple type zinc fingers Znf360基因全长4031个碱基,含8个外显子,在基因组dna上长17 . 3kb ,其编码蛋白质全长977个氨基酸,含一个krab框、一个scan框、两个sant框和10个kr pple型的锌指。 |
| 9. | The former four genes were belonged to krupple - type zinc finger family and irxl was belonged to iroquois homeobox family . both of the families are transcription factors . it was shown that the two family proteins are involved in the cardiogenesis process or cardiac disease 前面4个基因属于c2h2 -型锌指蛋白家族, irx1属irx蛋白家族,它们都是转录因子,研究表明这两个家族蛋白都参与心脏的发育或疾病发生过程。 |
| 10. | So it is response to the exogeneous hoemones at an early stage . hormones are essential for maintaining the expression of hrz , a ring zinc finger gene . hrz expresses in the explants cultured with hormones for 10 days and the level of expression is declined at day 15 因此, hzfj在外源激素的作用下,只在较短的时间内表达水平提高,表明该基因是对外源激素响应的早期基回c环状锌指蛋白基因hrz在未培养的外植体中表达。 |